About Tresiba Insulin
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There are two ways. Insulin can interact with the human body – bolus and basal. Bolus insulin is a quick-acting insulin taken just before meals. It helps to provide glucose control to the body due to glucose spikes immediately after meals. Basal Insulin is longer-acting and helps to release Insulin at a steady level throughout the day.
Basal Insulin means background insulin and mimics the human pancreas, where basal Insulin is absorbed by the body slowly throughout the day. Basal Insulin helps manage glucose levels in the blood for type 2 diabetic patients. A single dose is given for the entire day.
Tresiba Insulin 3x3ml is a once-daily injectable to improve glycemic control for adults with type 2 diabetes as an adjunct to diet and exercise. Insulin Tresiba 3x3ml is insulin degludec and is a long-acting Glucagon-like Peptide-1 (GLP-1) receptor agonist. Insulin degludec is a long-acting basal insulin. It will release more Insulin in the blood as the blood glucose increases, and the release of Insulin decreases as the demand for Insulin in the body reduces.
Do not share Tresiba Insulin 3x3ml pen or the needle with others, even if the hand has been changed.
Tresiba Insulin is available in 2 concentrations (U-100 and U-200):
- TRESIBA U-100 is a FlexTouch pen and multiple-dose vial and can deliver up to 80 units in a single injection.
- TRESIBA U-200 is a FlexTouch pen and can deliver up to 160 units in a single injection.
Warnings and Precautions of using Tresiba Insulin
- Hyperglycemia or Hypoglycemia
- Overdose Due to Medication Errors – check the label before each injection
- Acute Kidney Injury: Usually in association with nausea, vomiting, diarrhea, or dehydration – contact your doctor immediately
- Hypersensitivity and Allergic Reactions – Severe, life-threatening, generalized allergies, including anaphylaxis, angioedema, bronchospasm, hypotension, and shock, can occur with insulins.
- Hypokalemia (Potassium deficiency) – May cause respiratory paralysis, ventricular arrhythmia, and death.
- Fluid Retention and Congestive Heart Failure – discontinue the medication.
Symptoms of Hypoglycaemia may include:
- dizziness or light-headedness
- blurred vision
- anxiety, irritability, or mood changes
- sweating
- slurred speech
- hunger
- confusion or drowsiness
- shakiness
- weakness
- headache
- fast heartbeat
- feeling jittery
Adverse Reactions while using Tresiba Insulin
The most common adverse reactions reported are:
- Nasopharyngitis
- Headache
- Nausea
- Diarrhea
- Sinusitis
- Increased lipase and upper respiratory tract infection.
- Delay of gastric emptying.
What is dosage of Tresiba Insulin?
- In adults, inject Tresiba Insulin subcutaneously once daily at any time of day.
- In pediatric patients, inject Tresiba Insulin subcutaneously once daily at the same time every day
- The recommended days between dose increases are 3 to 4 days.
- Dosage adjustment is needed when there is a change in
- physical activity
- changes in meal patterns
- changes in renal or hepatic function
- during acute illness to minimize the risk of hypoglycemia or hyperglycemia
- Missing doses
- For adult patients, keep a minimum of 8 hours between two injections when awake.
- Inform your doctor and monitor patients.
- For type 1 patients, Tresiba Insulin must be used concomitantly with short-acting Insulin.
- Your doctor will prescribe medication.
Tresiba is a clear and colorless solution and is available in these formats:
- 100 units/mL (U-100): 3 mL single-patient-use Tresiba Insulin FlexTouch prefilled pen,
- 100 units/mL (U-100): 10 mL multiple-dose Tresiba Insulin vial
- 200 units/mL (U-200): 3 mL single-patient-use Tresiba Insulin FlexTouch prefilled pen
How to store Tresiba Insulin?
– Not used
- Refrigerated between 36°F to 46°F (2°C to 8°C) until expired.
- At room temperature (up to 86°F [30°C]) for 56 days.
– Used
- Room Temperature or Refrigerated for 56 days.
Remember that regular physical exercise is crucial to treating diabetes or managing prediabetes, along with your diet planning, weight management, and medications. Because your cells become more responsive to insulin while you are active, your blood glucose, also known as blood sugar, can be lowered more successfully. Take your medications regularly and follow up with your healthcare specialist.
